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How Avantor and Aera Technology Are Operationalizing Decision Intelligence, Insights from ARC Advisory Group’s 30th Leadership Forum
Published
2 mois agoon
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During the 30th Annual ARC Advisory Forum on February 10th, the session “The New Frontier of Operations and Supply Chain” offered 1.5 hours of valuable learning. It provided a platform for professionals to share their experiences and insights about the future of supply chains. The session delved into real-world end-user case stories, high-level discussions on implementing innovative solutions, and integrating AI into operational processes.
How Avantor Got Started on Its Decision Intelligence Journey
Jared Guckenberger was the end-user presenter during the session, showcasing the results of implementing Aera Technology’s Decision Intelligence solution. Jared is the VP of Global Supply Chains at Avantor. Avantor provides mission-critical materials and tools to life science companies, biopharmaceutical producers, and medical R&D organizations. Avantor has a global reach of 175 countries, 40 distribution centers, plus various college closet storage sites.
Scale:
10,000 supplier/ source combinations
250,000 SKUs sold per year
1.5 SKU-location combinations
10M+ purchase + customer orders per year
Jared shared Avantor’s supply chain challenges, including very high transaction and data volumes. Inventory challenges: too much, too old, and too little at the same time (excess, write-offs, and stockouts). Jared expressed the need to sense, decide, and act faster: integrate better with suppliers (many are low-tech, non-EDI). Many solutions must be “change-ready”, scalable, and usable by many roles, not fully autonomous AI.
Jared played a pivotal role in establishing a working relationship with Aera Technology to address the company’s supply chain challenges by utilizing Aera’s Decision Intelligence solution. It’s not only “Agentic Ai but also classic machine learning, decision logic, which are all orchestrated into repeatable decision processes. The core idea of Decision Intelligence is that it lets the system make thousands of routine decisions humans don’t have time for, rather than “smarter than humans” decisions.
At the start, Avantor focused on three reasonable target skill areas, focusing on decisions and processes that were traditionally inefficient. Avantor focused on stock rebalancing, purchase order cancellation, and purchase order prioritization to address inventory issues and improve customer service.
Stock Rebalancing: In the past, it was largely a manual, monthly exercise with lots of churn, and distribution centers were reluctant to spend days loading trucks; only top items were prioritized. Now: System scans twice a week to find dead or slow-moving stock and target locations with demand. DI produces move recommendations: planners approve or reject. On approval, stock transport orders are created in SAP automatically. The overall impact includes moving from infrequent “chunks to continuous, every other day rebalancing. Captures many “small” opportunities humans previously ignored: reduces write-offs and dead stock.
Purchase Order Cancellation: Traditionally, dynamic demand (orders canceled or changed) had a slow response time of 2-3 weeks. Now, systems scan weekly and propose PO cancellations. They send recommendations to suppliers via email (no EDI required). Suppliers reply by email; the system parses the response and summarizes it. The buyer then decides whether to accept or deny the cancellation. This process has reduced the cycle time from weeks to about a week or less. In the early phase, this approach has already saved $300K in inbound POs within 1-2 weeks using a small group.
Purchase Order Prioritization: Avantor has transitioned from a reactive to a proactive approach to managing stockouts. Now: The new system predicts potential stock shortages based on current demand and supply data. It then automatically emails vendors with requests like, “Can you move this delivery up by C days?” The vendor’s response (yes, no, or partial) is processed by the system and presented to the buyer, who then confirms the changes after considering associated costs. This proactive service enhancement improves the customer experience without relying on Advanced Planning and Scheduling (APS) tools like SAP.
Key Takeaways:
“Don’t wait for perfection; go live, then iterate.” Avantor currently has 62 enhancements still in the backlog. Pick skills with clear, immediate business impact and strong business sponsorship. Simplify processes where possible before or alongside automation. Lastly, have a roadmap ready: successful pilots quickly create demand for more AI/decision-intelligence use cases, which must then be prioritized and funded.
Executive Leadership Q&A Discussion:
After the presentation portion of the session, we moved into a Q&A style format with various industry professionals, including:
Peter Quimby of Aera Technology
Jeremy Hudson of Open Sky Group
Bryan Batchelder of Datex
Jared Guckenberger of Avantor
With over an hour of discussion, here are some of the top-line questions and answers from our panelists.
Question 1: As a system integrator, what best practices should customers follow when integrating new solutions, especially around data and AI?
Jeremy Hudson responded that many prospects want to attack the “gnarliest” use cases or copy flash keynotes (digital twins, robots, etc). Jeremy suggests you start with the simple, high-impact problems (where not everyone sends ASNs/EDI) rather than trying to boil the ocean. Focus on supporting decision makers, accept that data won’t be perfect, and choose tools that can work with and around bad data.
Question 2: How do you handle a go-live when the system isn’t perfect yet? Did you run a parallel (head-to-head) system, and how did you manage the risks?
Jared responded that there was no parallel legacy system because they had zero systems to begin with, so they could not do a clean head-to-head comparison. He also added that there was a “steering team” which was set up to communicate extensively with their distribution network. Citing an example of having to explain that spending $15 on UPS to avoid losing $1,000 in inventory.
Peter Quimby added that this is about Decision Intelligence, explicitly designing, evaluating, and learning from decisions. You “bring some eggs to make the omelet”: accept early friction to start capturing learning signals.
Question 3: Bryan, your role at Datex is part back-end developer and front-end product manager. What capabilities have you been recently working on, and how have your customers responded?
Bryan spoke in great detail about how the Datex platform is built on a low-code app platform that enables professional services teams to implement customizations faster and more cost-effectively. Additionally, some capabilities that Bryan is working on include embedding AI and agentic coding tools to help users define data sources (essentially queries over the data), which enables those data sources to be wrapped into reports. Lastly, they are striving towards building their own multi-agent orchestration and execution environment. Which would essentially mean that their customers would have their own agent that is loaded with all available context from sales prospectability to post-implementation debriefs.
Final Thoughts:
The session highlighted the current thinking and actions of leading companies in the supply chain market. A paradoxical trend is emerging: a significant rise in disruptions is occurring alongside the achievement of new levels of operational efficiency. Both end-users and providers are navigating distinct challenges, yet they share the common goals of increasing resilience and efficiency, and maintaining a competitive edge through digital transformation.
The post How Avantor and Aera Technology Are Operationalizing Decision Intelligence, Insights from ARC Advisory Group’s 30th Leadership Forum appeared first on Logistics Viewpoints.
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The OSI Model and AI in the Supply Chain: Why Layered Architecture Still Matters
Published
15 heures agoon
14 avril 2026By
AI in the supply chain is often approached as an application problem. In practice, it is more often an architectural one. The OSI model offers a useful lens for understanding why.
The Architecture Problem Behind AI in Supply Chains
Most discussions about AI in the supply chain begin at the top of the stack. They focus on copilots, models, dashboards, and use cases such as forecasting, routing, and risk detection. Those applications matter, but they are not the starting point.
The more important issue is the architecture underneath them.
This is where the OSI model becomes a useful reference point. Not because supply chains operate like communications networks in any literal sense, but because the OSI model solved a similar structural problem. It separated complexity into layers and clarified how those layers interact. That same discipline is becoming increasingly relevant as AI moves deeper into logistics and supply chain operations.
AI in the Supply Chain Is Best Understood as a Layered System
The most practical way to think about AI in the supply chain is as a layered system.
At the foundation is the data layer. This includes ERP, TMS, WMS, IoT signals, supplier feeds, and external data sources. If this layer is fragmented or inconsistent, the layers above it will underperform. That aligns directly with the data harmonization requirement described in ARC research. AI depends on clean, linked, and current data, and advanced systems are only as effective as the data they operate on .
Above that is the communication layer. In traditional systems, applications exchange information through rigid integrations, manual handoffs, and batch processes. In more advanced environments, data and decisions move through APIs, event streams, and increasingly through agent-to-agent coordination. ARC’s framework describes A2A as a way for autonomous software agents to interact directly, share data, assess options, and execute decisions across the supply chain . That matters because modern supply chains do not just need better analytics. They need faster coordination across functions.
Context Is the Missing Layer in Many AI Deployments
The next layer is context. This is where many AI initiatives begin to weaken. Systems may generate plausible recommendations, but without memory of prior events, supplier history, operational constraints, or previous failures, they remain limited. The white paper describes the Model Context Protocol as a way to embed memory, identity, and continuity into AI systems so they can retain operating context over time and carry that context across workflows . In supply chain settings, that kind of continuity is important because decisions are rarely isolated. They are part of a sequence.
Reasoning Must Reflect the Networked Nature of Supply Chains
Then comes the reasoning layer. This is where retrieval-augmented generation and graph-based reasoning become useful. RAG allows systems to retrieve current, domain-specific information before generating an answer. Graph RAG extends that by reasoning across interconnected entities and dependencies. ARC’s analysis makes the point clearly: supply chains are networks, not lists, and graph structures help AI navigate those interdependencies more effectively .
This is one of the more important distinctions in enterprise AI. A system that can retrieve a policy document is useful. A system that can understand how a supplier, a port, an order, and a downstream constraint relate to one another is more operationally relevant.
Why Many AI Initiatives Stall
At the top is the application layer, the part users actually see. This includes control towers, planning workbenches, copilots, and workflow assistants. Most companies start here. That is understandable, because this is the visible part of the stack. It is also why many AI initiatives produce narrow results. The application may improve, but the lower layers remain weak.
That is the main lesson the OSI analogy helps clarify. AI in the supply chain should not be treated primarily as a front-end feature. It is better understood as a layered architecture that depends on data quality, system interoperability, context retention, and network-aware reasoning.
This also helps explain why some AI deployments perform well in demonstrations but struggle in operations. The model itself may be capable, but the environment around it may not be ready. Data may not be harmonized. Systems may not communicate cleanly. Context may not persist. Knowledge retrieval may not be grounded in current enterprise information. In those cases, the problem is not that AI has limited potential. The problem is that the stack is incomplete.
The ARC Framework Points to a More Durable Model
The ARC framework points toward a more grounded view. A2A supports coordination between systems. MCP supports continuity across time and decisions. RAG supports access to relevant knowledge. Graph RAG supports reasoning across a networked operating environment. Together, these are not just features. They are components of an emerging architecture for supply chain intelligence.
What This Means for Supply Chain Leaders
For supply chain leaders, the implication is practical. AI strategy should begin with the question, “What layers need to be in place for these systems to work reliably at scale?” That shifts the focus away from isolated pilots and toward a more durable operating model.
In practical terms, that means improving data harmonization before expanding model deployment. It means designing for system-to-system coordination rather than relying only on dashboards and alerts. It means treating context as infrastructure rather than as a convenience feature. And it means building toward reasoning systems that reflect the networked nature of the supply chain itself.
Bottom Line
The OSI model is not a blueprint for AI in logistics. But it remains a useful reminder that complex systems tend to perform better when their layers are clearly defined and properly integrated.
That is becoming true of AI in the supply chain as well.
The companies that recognize this early are more likely to build systems that support better coordination, more consistent decision-making, and more useful intelligence across the network. The companies that do not may continue to add AI applications at the surface while leaving the underlying architecture unresolved.
The post The OSI Model and AI in the Supply Chain: Why Layered Architecture Still Matters appeared first on Logistics Viewpoints.
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Anthropic’s Mythos Raises the Stakes for Software Security
Published
15 heures agoon
14 avril 2026By
Anthropic’s decision to restrict access to Mythos is more than a product decision. It suggests that frontier AI is moving into a more serious class of cybersecurity capability, with implications for software vendors, critical infrastructure, and the digital systems that support modern supply chains.
Anthropic’s latest announcement deserves attention well beyond the AI market.
The company says its new Claude Mythos Preview model has identified thousands of previously unknown software vulnerabilities across major operating systems, browsers, and other widely used software environments. But the more important point is not the claim itself. It is the release strategy. Anthropic did not make the model broadly available. It placed Mythos inside a controlled early-access program and limited access to a select group of major technology and security organizations.
That tells you something.
This is not being positioned as another general-purpose model that happens to be good at security work. Anthropic is treating Mythos as a system with enough cyber capability, and enough dual-use risk, to justify a restricted rollout. That is a notable change in posture.
For supply chain and logistics leaders, the relevance is not hard to see. Modern supply chains now depend on a thick software layer: ERP platforms, transportation systems, warehouse systems, visibility tools, APIs, cloud infrastructure, industrial software, and partner integrations. If frontier AI materially improves the speed and scale at which vulnerabilities can be found, then this is not just a cybersecurity story. It is an operations story.
A compromised transportation platform is not merely an IT issue. A weakness in a warehouse execution environment is not just a software problem. These failures can disrupt planning, fulfillment, supplier coordination, inventory visibility, and customer service. In a software-mediated supply chain, cyber weakness increasingly becomes operational weakness.
That is the real significance here.
Over the last year, much of the AI discussion has centered on productivity. Better copilots. Faster coding. More automation. Mythos is a reminder that the same capability gains can cut the other way too. A model that is better at reasoning through code and complex systems may also be better at finding weaknesses, chaining exploits, and shortening the gap between vulnerability discovery and exploitation.
That does not mean a disaster scenario is around the corner. But it does mean the discussion is changing.
There is also a second issue in Anthropic’s release strategy. Early access creates asymmetry. The organizations that get access to these tools first will be in a better position to harden their environments than those that do not. Large platform vendors and elite security firms are more likely to absorb this shift quickly. Smaller software providers and companies with less security depth may not.
That matters commercially as well as technically.
In a more AI-intensive security environment, resilience becomes a more visible part of product value. Customers will still care about features, workflow, and ROI. But they will also care, more directly, about whether a vendor can secure its software stack in an environment where advanced models may be able to surface weaknesses faster than traditional testing methods ever could. For some vendors, that will strengthen their position. For others, it may expose how thin their defenses really are.
There is also a governance signal here. A leading AI company has decided that broad release is not the responsible first step for this class of capability. Whether that becomes standard practice or not, it marks a threshold. It suggests that at least some frontier model capabilities now carry enough cybersecurity weight to influence how they are released and who gets access first.
Enterprise technology leaders should pay attention to that.
They should also take the broader lesson. Security cannot sit on the edge of the AI agenda. It has to move closer to the center of the operating model. That means tighter software supply chain governance, faster patching cycles, better dependency visibility, stronger segmentation of critical systems, and more disciplined red-teaming. It also means recognizing that cyber resilience is now part of business resilience.
There is a related point here. If models like Mythos increase uncertainty around software security, vendors will face a higher burden to prove resilience. If vulnerability discovery is getting faster and cheaper, then older assumptions about defensibility, testing depth, and incumbent safety become less comfortable. That pressure will not fall evenly. Firms with strong engineering depth and security discipline are more likely to absorb it. Others may find that the market becomes less forgiving.
For supply chain leaders, the takeaway is straightforward. As AI becomes more deeply embedded in planning, logistics, and execution systems, the integrity of the software environment becomes more central to performance. If frontier models accelerate vulnerability discovery, the burden on both vendors and enterprises to secure those environments rises with it.
Mythos matters not because it proves the worst case. It matters because it shows where the curve is going.
A major AI developer has now made clear that frontier AI is moving into territory where the cybersecurity implications are serious enough to shape release strategy and access controls. That is a meaningful development. Supply chain and technology leaders should treat it that way.
The post Anthropic’s Mythos Raises the Stakes for Software Security appeared first on Logistics Viewpoints.
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Autonomous Trucking Is Fragmenting Into Distinct Market Entry Models
Published
16 heures agoon
14 avril 2026By
Autonomous trucking is no longer a single category defined by technical ambition. It is fragmenting into distinct market entry models, each with different paths to commercialization, risk profiles, and timelines for impact on freight execution.
A Market No Longer Defined by One End State
Autonomous trucking is no longer a single race to full driverless operation. It is fragmenting into distinct entry models, each addressing a different part of the freight problem with different timelines, risk profiles, and economic logic.
For several years, the category was framed as a single end state: driverless trucks operating broadly across long-haul freight networks.
That framing no longer fits the market as it is developing.
What is emerging instead is a set of entry models, each aimed at a different operational problem. These models are not progressing on the same timeline, and they are not constrained by the same variables. For supply chain and logistics executives, that distinction matters more than tracking broad claims about autonomy.
This pattern is common in industrial technology. New capabilities rarely enter at the most complex point in the system. They enter where variability is manageable, the economics are clearer, and operational value can be demonstrated sooner.
Long-Haul Autonomy Remains the Full-Stack Ambition
The most visible model remains long-haul autonomous trucking. This is the original vision: driverless trucks moving across highway networks, reducing labor constraints and improving asset utilization.
The opportunity is substantial, but so are the requirements. These systems must operate safely at highway speed, handle weather and traffic variation, and meet a more demanding regulatory and operational standard than narrower autonomy use cases.
Companies such as Aurora, Kodiak, and Torc Robotics are pursuing this path with increasing focus on defined freight corridors and structured deployment plans. Rather than attempting broad geographic coverage too early, these companies are concentrating on lanes where conditions can be better controlled and performance can be measured with more discipline. Other entrants such as Waabi, Plus, and a range of OEM and infrastructure partners are advancing similar models across different segments of the market.
Middle-Mile Autonomy Offers a Faster Commercial Path
A second model has emerged with a different profile: middle-mile autonomy.
Instead of solving for open-ended highway networks, this approach focuses on repeatable routes between fixed nodes such as distribution centers, stores, and cross-dock facilities. The operating environment is still demanding, but the variability is lower and the economic case can be easier to establish.
Gatik is the clearest example of this model. Its approach reflects a practical reality in freight automation: autonomy does not need to solve the hardest problem first to create value. In many supply chains, middle-mile freight is frequent, predictable, and costly enough that even partial automation can improve network performance. This makes middle-mile autonomy one of the more credible early commercial entry points.
Yard and Terminal Autonomy Benefit From Bounded Environments
A third model is taking shape in yards, terminals, and other bounded environments.
Here, the domain is tighter, speeds are lower, and routes are more repetitive. That reduces deployment complexity and creates a more practical setting for automation to mature.
Outrider is an example of how this strategy is developing. Yard operations are often overlooked in broader autonomy discussions, but they matter. Delays at this stage affect linehaul schedules, dock utilization, and downstream fulfillment performance. As a result, yard autonomy may scale earlier than more ambitious highway programs, not because it is more important, but because it is operationally easier to implement.
Hybrid and Teleoperated Models Create a Bridge
Between fully manual operations and fully autonomous systems, hybrid models are also emerging.
These combine onboard automation with remote human intervention, allowing systems to handle routine tasks while escalating exceptions when needed. This approach lowers deployment risk and gives operators a way to build confidence without requiring immediate full autonomy in all conditions.
FERNRIDE reflects this bridging strategy. Its relevance is not just technical. It points to a broader truth about the category: the path to autonomy is likely to be incremental in many freight environments. Hybrid models can help carriers and shippers introduce automation in a way that fits operational reality rather than forcing a binary shift from manual to driverless.
OEM Integration May Determine Who Scales
Another important path is OEM-integrated autonomy.
In this model, autonomous capabilities are built into commercial vehicle platforms through close alignment with truck manufacturers and industrial partners. This matters because scaling freight autonomy is not only a software challenge. It is also a manufacturing, maintenance, service, and support challenge.
That is why partnerships involving companies such as Plus, Daimler Truck, Volvo Autonomous Solutions, and other OEM-linked players deserve attention. Industrialization will play a major role in determining which autonomy programs remain pilot-stage efforts and which ones become durable components of freight networks.
What This Fragmentation Means
Taken together, these entry models point to a broader conclusion. Autonomous trucking is not arriving as a single unified capability. It is entering the market through multiple constrained domains, each built around a different balance of technical feasibility, operational complexity, and economic return.
That fragmentation is a sign of market maturation. The industry is moving away from generalized ambition and toward deployment strategies grounded in specific use cases. Long-haul autonomy targets the largest long-term opportunity. Middle-mile autonomy prioritizes repeatability and faster commercialization. Yard autonomy benefits from bounded environments. Hybrid models provide a bridge. OEM-integrated approaches provide the industrial foundation needed for scale.
What Supply Chain Leaders Should Watch
For supply chain leaders, the practical question is no longer whether autonomous trucking will arrive. It is where it will enter the network first, under what operating model, and with what operational implications.
In some cases, the answer will be a middle-mile loop between fixed facilities. In others, it will be yard movements, teleoperated support, or corridor-based long-haul deployment.
The larger point is architectural. These systems will not create value in isolation. They depend on data, orchestration, and coordination across the broader freight technology stack. In that sense, autonomous trucking is one more example of the broader shift toward connected, intelligent supply chain execution described in ARC’s recent work on AI architecture in logistics.
Where Tesla Fits
Tesla is better treated as an adjacent company to watch rather than a central example. The Tesla Semi is relevant to the future of freight equipment, but Tesla’s current positioning emphasizes electrification and supervised driver-assistance rather than a clearly defined autonomous freight deployment model.
Closing Perspective
Autonomous trucking will not arrive all at once. It will enter the supply chain through specific lanes, nodes, and operating models where the economics and constraints align.
The competitive advantage will not come from adopting autonomy broadly, but from understanding where it fits first and integrating it into the network ahead of competitors. That is where the category becomes operational, and where it begins to matter.
The post Autonomous Trucking Is Fragmenting Into Distinct Market Entry Models appeared first on Logistics Viewpoints.
The OSI Model and AI in the Supply Chain: Why Layered Architecture Still Matters
Anthropic’s Mythos Raises the Stakes for Software Security
Autonomous Trucking Is Fragmenting Into Distinct Market Entry Models
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